对医生和患者的生成人工智能的应用瘤学 Letters-AI-OncLetters
Adel Shahnam1, Udit Nindra2, Nadia Hitchen1
1Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
JCO clinical cancer informatics
|May 2, 2025
概括
像ChatGPT这样的大型语言模型可以在瘤学中生成准确的医生和患者信件. 虽然通常是安全和可理解的,但为了最佳的临床使用,需要在细节和流量方面进行微小的改进.
科学领域:
- 医学瘤学 医学瘤学
- 医疗保健中的人工智能
- 临床交流 临床沟通
背景情况:
- 大型语言模型 (LLM) 在临床环境中表现有前途,但它们在医学瘤学中的有效性需要正式评估.
- 评估LLMs的质量,准确性和有效性对于生成临床文档至关重要.
研究的目的:
- 评估ChatGPT在从瘤学临床病例笔记中生成医生和患者信件的能力.
- 评估人工智能生成的医疗通信的准确性,相关性,可读性和安全性.
主要方法:
- 瘤学家创建了合成瘤病例笔记,以便快速开发和生成信件.
- 通过ChatGPT生成的医生和患者信件被瘤学家和消费者使用利克特尺度评估.
- 患者的信件进一步使用患者教育材料评估工具 (PEMAT-P) 和可读性指数进行了评估.
主要成果:
- 95%的瘤学家认为医生信非常准确,全面和相关,没有安全问题.
- 患者的信件达到七年级的阅读水平和高可理解度得分 (PEMAT-P>80%).
- 虽然通常是明确的,但一些患者的信件有轻微的遗漏和风格不一致;72%的消费者会接受人工智能生成的信件.
结论:
- 通过结构化的提示,ChatGPT产生高质量的临床和患者通信信件,符合既定标准.
- 没有发现临床安全问题,但建议对细节和自然语言流量进行改进.
- 进一步研究将人工智能生成的和人类写的字母进行比较是有必要的,以优化实践中的实用性.
相关概念视频
02:50Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K
01:29Issues And Trends In Healthcare Delivery System
5.5K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.5K
01:21Cancer Survival Analysis
291
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
291
01:27Tumor Immunotherapy
397
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
397
02:56Treatment Resistant Cancers
3.2K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.2K