在接受上达西提尼布治疗的青少年中传播的巴顿氏菌病和EBV复激活
Vincent Pargny1, Emilie Delugre2, Raphael Janela3
1Pediatrics Department, Rouen University Hospital, France; Infectious Diseases Department, Rouen University Hospital, France.
概括
一名15岁的男性接受了乌帕达西提尼布的治疗,患上了传播的巴顿氏菌病. 这一案例凸显了在接受JAK抑制剂的患者中严重细菌感染和病毒再激活的风险.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
背景情况:
- 巴托内拉汉塞拉会在免疫力低下的人群中引起传播性感染.
- 乌帕达西尼布是一种Janus激酶 (JAK) 抑制剂,已被批准用于青少年严重的亚托皮炎.
- 这份报告详细介绍了一例15岁男性的病例,该病例是用upadacitinib治疗的.
相关概念视频
Immunodeficiency Diseases
3.7K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
3.7K
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
755
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
755


