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Updated: May 23, 2025

Human Pluripotent Stem Cell Culture on Polyvinyl Alcohol-Co-Itaconic Acid Hydrogels with Varying Stiffness Under Xeno-Free Conditions
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矩阵刚度通过DNA甲基化调节hPDLSCs的骨质分化

Rong Ding1, Chen Chen1, Ling Wang1

  • 1Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China; Clinical Research Centre of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China; College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.

International dental journal
|May 2, 2025
PubMed
概括

更硬的基底通过增加DNA甲基化来增强人类牙周带干细胞 (hPDLSCs) 的骨质分化. 这种表观遗传机制对于理解牙在正牙科期间的牙运动至关重要.

关键词:
通过DNA甲基化.在DNA甲基转移酶中.矩阵的刚度 矩阵的刚度骨质分化的骨质分化在hPDLSC中使用.

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