没有感染,恶性病变或免疫功能障碍的住院患者的白血计数
Yazan Abu Omar1, Erin Sullivan2, Rebecca Schulte3
1From the Department of Hospital Medicine.
Southern medical journal
|May 2, 2025
概括
没有感染或恶性病症的住院患者的正常白细胞 (WBC) 计数为1.6-14.5 × 10^9 WBCs/L. 诸如年龄,种族和并发症等因素会影响该人群中的WBC计数.
科学领域:
- 临床医学 临床医学
- 血液学 血液学 血液学
- 实验室医学 实验室医学
背景情况:
- 升高的白细胞 (WBC) 计数可以表明严重的健康问题,如恶性瘤,感染或免疫功能障碍.
- 目前的诊断实践依赖于从健康人群中获得的参考范围,这些范围可能不准确地反映住院患者.
- 目前缺乏针对没有这些疾病的住院患者的WBC计数的具体参考范围.
研究的目的:
- 为了确定住院患者白细胞 (WBC) 计数的正常参考范围.
- 在没有恶性瘤,感染或免疫功能障碍的住院患者中确定影响WBC计数的因素.
主要方法:
- 在2017-2018年46,419名非手术性住院患者进行了回顾性横截面研究.
- 收集的数据包括白细胞计数,绝对中性粒细胞计数和绝对淋巴细胞计数.
- 计算了WBC计数的平均值,标准偏差和参考范围.
主要成果:
- 在这个队列中,白细胞计数的正常参考范围被确定为1.6-14.5 × 10^9 WBCs/L.
- 老年,黑人种族和充血性心力衰竭等因素与较低的白细胞计数有关.
- 较高的白细胞计数与增加的体重指数,糖尿病,慢性脏病,慢性阻塞性肺病和类固醇使用有关.
结论:
- 没有感染,恶性或免疫功能障碍的住院患者的确定的正常白细胞计数范围是1.6-14.5 × 10^9 WBCs/L.
- 在解释WBC计数时,医生应考虑患者的人口统计学,并发病症和药物使用情况.
- 住院患者的白血球计数在11到14.5×10^9白血球/L之间可能被认为是正常的,需要谨慎解释.
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