梅皮瓦卡因对比布皮瓦卡因脊柱麻醉在全膝关节整形术后恢复运动功能:一个随机对照试验
Clinton F Pillow1, Carey Brewbaker2, Bethany J Wolf3
1Department of Anesthesiology and Perioperative Medicine, Medical University of South Carolina, Charleston, South Carolina, USA pillow@musc.edu.
Regional anesthesia and pain medicine
|May 2, 2025
概括
脊柱麻醉与mepivacaine加速了膝关节关节整形术后的运动功能恢复,但没有显著改善行走或当天出院率. 与梅皮瓦卡因一起观察到更低的尿率.
科学领域:
- 整形外科 整形外科 整形外科
- 麻醉学 麻醉学
- 外科手术的结果
背景情况:
- 越来越多的人要求在同一天出院,并在膝盖关节整形术后提前行走.
- 使用梅皮瓦卡因与布皮瓦卡因的脊柱麻醉可能会增强运动功能的恢复.
- 对于膝关节关节整形术患者,存在有限的随机试验.
研究的目的:
- 为了评估脊柱梅皮瓦卡因是否会导致较早的运动功能恢复.
- 评估梅皮瓦卡因对出行和当天出院的影响.
- 在膝关节关节整形手术患者中比较美皮瓦卡因与布皮瓦卡因.
主要方法:
- 163名接受初级全膝关节整形手术的患者被随机分类.
- 这些组接受了脊髓美皮瓦卡因 (60毫克) 或布皮瓦卡因 (10毫克).
- 主要结局:恢复运动功能的时间;次要结局:行走,放电,疼痛和副作用.
主要成果:
- 梅皮瓦卡因组显示了较快的运动功能的恢复 (210比229分钟,p<0.001).
- 梅皮瓦卡因组的尿率较低 (36%与57%相比,p=0.007).
- 在行走,当天出院,停留时间或阿片类药物消费方面没有显著差异.
结论:
- 脊柱美皮瓦卡因在膝关节整形术后加速了运动功能的恢复.
- 没有达到临床显著的20%的运动功能的恢复时间减少.
- 在麻醉组之间,行走时间和当天出院率在麻醉组之间是相似的.
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