在高海拔安第斯人群中患有类风湿关节炎的心血管风险得分之间的协议
Carlos Diaz-Arocutipa1, Vidia Lumbe-Diaz2, Percy Soto-Becerra3
1Unidad de Revisiones Sistemáticas y Meta-análisis (URSIGET), Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru.
Reumatologia clinica
|May 2, 2025
概括
心血管风险得分在风湿性关节炎患者中显示出显著的分歧,影响了高风险的识别. 需要进一步的研究来验证预后表现,以更好地管理患者.
科学领域:
- 类风湿病学 类风湿病学
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 类风湿性关节炎 (RA) 与心血管疾病 (CVD) 风险增加有关.
- 准确评估心血管疾病风险对于管理RA患者至关重要.
- 现有的心血管风险评分在RA群体中可能表现不同.
研究的目的:
- 评估风湿性关节炎 (RA) 患者三个主要心血管风险得分之间的一致性.
- 为了比较2019年世界卫生组织心血管风险评分 (2019-WHO-CRS),弗雷明汉风险评分 (FRS) 和风湿性关节炎 (ERS-RA) 扩大心血管风险预测评分在安第斯RA队列中的表现.
主要方法:
- 在秘鲁库斯科,对145名成人RA患者进行横截面研究.
- 使用2019-WHO-CRS,FRS和ERS-RA计算10年心血管疾病风险.
- 使用布兰德-阿尔特曼图表和卡帕统计数据评估得分协议.
主要成果:
- 在2019年WHO-CRS,FRS和ERS-RA之间观察到显著的分歧.
- 被归类为高风险 (>10%) 的患者比例差异很大:7.6% (2019-WHO-CRS),16.7% (FRS) 和23.2% (ERS-RA).
- 高风险预测的最高一致性是在2019年WHO-CRS和FRS之间 (卡帕:0.56).
结论:
- 选择的心血管风险评分显示,在识别患有RA的高风险个体方面存在相当大的变化.
- ERS-RA确定了最高比例的高风险患者.
- 前性研究对于确定RA患者这些评分的预后准确性至关重要.
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