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Updated: May 8, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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在AKAP11中异构性功能丧失突变的转录和表观基因组后果,AKAP11是双相情感障碍和精神分裂症的共同风险基因

Nargess Farhangdoost1,2, Calwing Liao3,4,5, Yumin Liu2,6

  • 1Department of Human Genetics, McGill University, Montreal, QC, Canada.

Molecular psychiatry
|May 2, 2025
PubMed
概括

功能丧失突变破坏了人类神经元中的基因表达和染色质,影响了与双极性障碍和精神分裂症相关的途径.

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