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Updated: May 8, 2025

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells
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Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells

Published on: January 29, 2019

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巨细胞通过VISTA抑制三阴性乳腺癌中CD8+T细胞细胞毒性功能

Maidinaimu Abudula1, Yuliana Astuti1, Meirion Raymant1

  • 1Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

British journal of cancer
|May 2, 2025
PubMed
概括

在三阴性乳腺癌 (TNBC) 中阻断V域Ig抑制T细胞激活 (VISTA) 增强了抗瘤免疫力. 这种免疫检查点阻塞会逆转巨细胞的免疫抑制,并增强T细胞活性,提供了一个有前途的治疗策略.

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