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导航风险:从两个沙特中心的无关海外脏移植的见解
Hany M El Hennawy1, Omar Safar2, Abdullah S Al Faifi3
1Surgery Department, Section of Transplantation, Armed Forces Hospitals, Khamis Mushayte, Southern Region 101, KSA, Saudi Arabia. hennawyhany@hotmail.com.
BMC nephrology
|May 2, 2025
概括
与当地手术相比,在国外进行的商业移植会导致更糟糕的结果和更低的移植存活率. 应该对患者进行风险教育,并促进已故器官捐赠,以减少这种做法.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 公共卫生 公共卫生
背景情况:
- 缺少用于移植的尸体器官促使沙特患者寻求在海外进行商业移植.
- 在国外进行移植 (KT) 经常与患者不良结果有关.
- 本研究检查了两家沙特移植中心在国际上进行的无关KT方面的经验.
研究的目的:
- 为了比较沙特患者在国外接受商业KT和接受当地生活无关KT的患者之间的术后结果.
- 使用回归分析,比较两组之间的累积移植存活率.
主要方法:
- 追溯性比较队列研究.
- 包括在2017年9月至2024年7月期间在国外 (I组) 接受商业化康复治疗的患者和与当地生活无关的康复治疗 (II组) 的患者.
- 对所有被纳入的患者进行至少一年的随访.
主要成果:
- 与II组 (本地KT) (7.9天) 相比,I组 (商业海外KT) 的住院时间明显长30天 (9.4天).
- 在第一组 (83.3%) 与第二组 (93.5%) 相比,初级功能移植率较低.
- 第一个组显著增加了手术部位感染,淋巴细胞和尿路感染的发生率. 与II组相比,I组的中期移植存活率较低 (5年存活率:54%),而II组 (5年存活率:60%).
结论:
- 与传统的无关移植相比,在国外进行的商业移植与移植存活率较低和整体结果较差有关.
- 关于海外KT的风险的患者教育至关重要.
- 建议促进公开注册已故器官捐献,以减轻商业移植的做法.
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