长期COVID-19嗅觉功能障碍患者的心理困扰
Manon Louvrier1, Sven Saussez1,2, Jerome R Lechien1,3,2,4
1Division of Laryngology and Broncho-esophagology, Department of Otolaryngology-Head Neck Surgery, EpiCURA Hospital, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.
长期的COVID-19嗅觉功能障碍 (OD) 与显著的心理痛苦有关,包括更高的抑郁和焦虑率. 这些心理健康状况需要在COVID-19后持续嗅觉丧失的患者中进行调查.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- 持续的嗅觉功能障碍 (OD) 是COVID-19的一个已知的长期后果.
- 心理压力,包括焦虑和抑郁,可能与慢性健康状况有关.
- 长期COVID-19相关的OD对心理健康的具体影响需要进一步阐明.
研究的目的:
- 调查COVID-19后持续超过六个月的嗅觉功能障碍 (OD) 患者经历的心理痛苦.
- 为了比较长期OD患者和无症状个体之间的心理结果.
主要方法:
- 从2023年8月到2024年1月招募OD>6个月的患者.
- 使用嗅觉障碍问卷 (ODQ) 和门,识别和歧视 (TDI) 测试进行嗅觉评估.
- 使用一般焦虑障碍 (GAD-7) 和患者健康问卷 (PHQ-9) 尺度进行心理痛苦评估.
主要成果:
- 与无症状对照组相比,持久性OD患者的GAD-7和PHQ-9得分显著更高.
- 在OD患者中观察到轻度至重度抑郁症 (51.2%) 和焦虑症 (39.5%) 的更高患病率.
- 无神经与严重焦虑相关,症状严重程度 (ODQ,SNOT-22) 与抑郁和焦虑水平有关.
结论:
- 在COVID-19之后长期存在的嗅觉功能障碍与显著的心理痛苦有关.
- 在这个患者群体中,抑郁和焦虑症状很普遍,需要临床治疗.
- 需要进一步的研究来澄清长期COVID-19 OD和心理健康结果之间的因果关系.
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