Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Viral Recombination00:57

Viral Recombination

23.3K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.3K
Acute Pharyngitis01:30

Acute Pharyngitis

482
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
482
Vaccinations01:51

Vaccinations

44.1K
Overview
44.1K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

919
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
919
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

45.7K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.7K
Immunological Memory01:23

Immunological Memory

557
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
557

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Determinants of Severity in Pediatric Viral Lower Respiratory Tract Diseases From Emergency Department Presentation to Hospital Course.

The Pediatric infectious disease journal·2026
Same author

Early and high Influenza A circulation alongside reduced Respiratory Syncytial Virus prevalence during autumn 2025 in paediatric patients attending emergency department.

Italian journal of pediatrics·2026
Same author

Expanding Diagnostic Options for Pediatric Meningitis: BCID2 Testing Results on Cerebrospinal Fluid After a Negative Meningitis/Encephalitis Panel.

Antibiotics (Basel, Switzerland)·2026
Same author

Epidemic cycles and post-epidemic decline of Mycoplasma pneumoniae in Italian children: implications for empirical macrolide prescribing.

Infection·2026
Same author

Disease Severity of Respiratory Syncytial Virus Infection in Hospitalized Children.

Viruses·2026
Same author

Has the COVID-19 outbreak put more children and adolescents at risk for suicidality? A longitudinal insight of the phenomenon in psychiatrically hospitalized patients.

Psychology, health & medicine·2026
Same journal

Delineating RSV-A and RSV-B: Epidemiological Patterns, Diagnostics, Clinical Severity, and Preventive Approaches.

Journal of medical virology·2026
Same journal

Assessment of Residual-Serum SARS-CoV-2-N-Antigen Testing for Hospital Surveillance in Germany.

Journal of medical virology·2026
Same journal

JQKD82 Inhibits HIV Infection of Macrophages Through Blocking Viral Entry and Enhancing Antiviral ISG Responses.

Journal of medical virology·2026
Same journal

Commentary on "Broadly Protective Antibody-Like Vaccines Against Highly Pathogenic Coronaviruses".

Journal of medical virology·2026
Same journal

Torque Teno Virus Dynamics in Plasma and BAL of COVID-19 ARDS Patients With and Without ECMO.

Journal of medical virology·2026
Same journal

Comprehensive Evaluation of the Elecsys HCV Duo Immunoassay for Active Hepatitis C Detection: Insights From the DEPCDUO Study.

Journal of medical virology·2026
查看所有相关文章

相关实验视频

Updated: Jun 12, 2025

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
13:47

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems

Published on: April 23, 2012

10.9K

帕尔沃病毒B19反弹反弹

Stefania Ranno1, Cristina Russo1, Luna Colagrossi1

  • 1Microbiology and Diagnostic Immunology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Journal of medical virology
|May 3, 2025
PubMed
概括
此摘要是机器生成的。

人类帕沃病毒B19 (B19V) 疫情正在增加,在2024年观察到的感染数量显著增加. 这导致了严重的后果,包括住院和死亡,特别是儿童和孕妇.

关键词:
B19病毒病毒B19病毒病毒流行病学流行病学免疫球蛋白是一种免疫球蛋白.感染的感染感染.帕尔沃病毒病毒.

更多相关视频

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

15.4K
An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

10.8K

相关实验视频

Last Updated: Jun 12, 2025

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
13:47

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems

Published on: April 23, 2012

10.9K
Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

15.4K
An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

10.8K

科学领域:

  • 病毒学 病毒学
  • 儿童传染病 儿童传染病
  • 流行病学 流行病学

背景情况:

  • 人类帕沃病毒B19 (B19V) 引起了一系列疾病,从无症状到危及生命的疾病.
  • 疫情发生周期性,最近的国际警报促使本次调查.
  • 了解B19V循环对于在疫情期间管理儿科健康至关重要.

研究的目的:

  • 分析B19V在第三级儿科医院的循环和临床影响.
  • 评估从2018年到2024年的B19V阳性率和临床结果.
  • 调查B19V在孕妇中的患病率及其对胎儿结果的影响.

主要方法:

  • 追溯分析了9695个血液样本,11个羊水和10827个血清.
  • 通过分子和血清学检测直接和间接检测B19V.
  • 在一组阳性样本上进行B19V亚型分析.

主要成果:

  • 与2018年 (9.8%) 和2023年 (0.8%) 相比,B19V年阳性率在2024年 (32.8%) 激增.
  • 在2024年,314名患者的检测结果呈阳性;65%患有初级感染,73.5%住院,11.3%需要接受ICU治疗.
  • 严重的结局包括心肌炎,心血管,神经和胃肠道病理,有两例儿科死亡;四种羊水检测呈阳性.

结论:

  • 在2024年观察到B19V循环的显著增加,导致严重的临床结果和住院治疗.
  • B19V感染影响了患有并发症和没有并发症的儿童,以及孕妇,对未出生的婴儿构成风险.
  • 仅检测到B19V亚型1A,具有较低的内基因型多样性,表明存在主导的循环菌株.