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在14614名人类乳头瘤病毒疫苗接种和未接种的丹麦年轻女性中比较风险行为

Maria Holst Algren¹, Amalie Timmermann¹, Palle Valentiner-Branth²

¹National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

|May 3, 2025

概括

年轻女性接种人乳头瘤病毒 (HPV) 疫苗与吸烟或过度饮酒无关. 虽然接种HPV疫苗的妇女使用非避孕套的比例较高,但这与年龄和避孕等因素有关,而不是疫苗本身.

科学领域:

公共卫生公共卫生
流行病学流行病学
疫苗学疫苗学疫苗学

背景情况:

人类乳头瘤病毒 (HPV) 是一种常见的性传播感染.
风险行为如不使用避孕套,吸烟和过度饮酒往往是集群的.
这些行为可能会增加HPV感染的风险.

研究的目的:

为了比较丹麦HPV疫苗接种和未接种的年轻女性之间的风险行为 (不使用避孕套,吸烟,过度饮酒).

主要方法:

利用了来自2019年丹麦国家青年研究的14614名年轻女性 (15-23岁) 的调查数据.
从丹麦疫苗注册表中提取了HPV疫苗接种状态.
采用多级物流回归来分析疫苗接种状态和风险行为之间的关联.

主要成果:

在HPV疫苗接种状态和吸烟或饮酒过度之间没有发现统计学上显著的关联.
最初,在接种疫苗的妇女中观察到更高的非避孕套使用率,但在调整后,这种情况减弱了.
在调整了人口统计学,社会经济因素,吸烟和过度饮酒后,接种疫苗的女性中,非避孕套的使用率高出21%,但当排除使用荷尔蒙避孕药的稳定关系的女性时,这种关联消失了.

结论:

在年轻女性中,HPV疫苗接种与吸烟或过度饮酒没有明显的关联.
接种疫苗的妇女中使用非避孕套的更高患病率可能是由年龄,关系状况和荷尔蒙避孕药的使用解释的,而不是疫苗.
这项研究表明,HPV疫苗接种不会导致更多的人参与其他冒险行为.

关键词:

过度饮酒过量饮酒过量饮酒过量饮酒过量饮酒过量饮酒过量饮酒人类乳头瘤病毒疫苗接种有风险的性行为.吸烟吸烟吸烟吸烟年轻人年轻人年轻人

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