揭示了在玉米幼苗中的耐受性背后的转录调节网络
Rui Wang1, Hualei Zhang1, Zihan Liu1
1The National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei 230036, China.
Journal of hazardous materials
|May 3, 2025
概括
(Se) 对植物生长至关重要,但在高水平下是有毒的. 这项研究揭示了控制玉米Se耐受性的遗传和表观遗传机制,确定了改善作物的关键基因和转录因子.
科学领域:
- 植物生物学 植物生物学
- 分子遗传学 分子遗传学
- 农业科学 农业科学
背景情况:
- (Se) 在植物中具有双重作用,作为一种必不可少的微量营养素和一种潜在的毒素.
- 了解Se耐受性机制对于作物弹性和生物强化至关重要.
研究的目的:
- 阐明管理玉米幼苗中Se反应的监管网络.
- 确定导致Se耐受性和适应性的遗传和表观遗传因素.
主要方法:
- 综合转录组学 (RNA-seq),染色质可访问性 (ATAC-seq) 和全基因组关联研究 (GWAS).
- 在不同度的Se下分析了剂量依赖的转录和表观遗传重编程.
- 描述了ZmGSTs基因家族的特征,并确定了关键的调控元素.
主要成果:
- 低Se增强了生长;高Se诱导了毒性和抑制了生长.
- 转录重编程涉及谷氨酸生物合成,Se代谢和莉酸 (JA) 信号,由染色体重塑协调.
- 确定ZmGSR2,ZmWRKY48,ZmbZIP123和ZmKNOX6对于Se代谢和耐受性至关重要.
结论:
- 这项研究为玉米中Se耐受性的遗传和表观遗传基础提供了新的见解.
- 确定了可以向改善作物Se适应性和生物强化的主要基因和转录因子.
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