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Updated: May 9, 2025

Author Spotlight: Enhancements in Gene Expression Regulation Research
07:10

Author Spotlight: Enhancements in Gene Expression Regulation Research

Published on: September 15, 2023

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长期的基因素乳化连接了先天免疫记忆中的代谢和表观遗传重新连接

Athanasios Ziogas1, Boris Novakovic2, Lorenzo Ventriglia3

  • 1Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Cell Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, the Netherlands.

Cell
|May 3, 2025
PubMed
概括

训练有素的免疫,是一种天生的免疫记忆,涉及诸如基因组乳化 (H3K18la) 的表观遗传变化. 这一与乳酸生产相关的过程增强了免疫反应,并在BCG疫苗接种后长期持续.

关键词:
一个BCG卡尔梅特 - 格林菌H3K18la 其他乳酸盐乳酸化被训练的免疫力

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