认知训练对帕金森病平衡和运动症状的影响:一项探索性随机对照试验
Aída Arroyo-Ferrer1,2, Marcos Moreno-Verdú2,3, Francisco José Sánchez-Cuesta1,2
1Faculty of Experimental Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Spain.
NeuroRehabilitation
|May 3, 2025
概括
对帕金森病 (PD) 的自我认知训练没有改善平衡或认知. 然而,它显著降低了运动症状的严重程度,这表明PD患者对运动功能的潜在益处.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 运动障碍 运动障碍
背景情况:
- 认知康复正在作为帕金森病 (PD) 认知和运动障碍的干预措施进行探索.
- 现有研究表明,在PD患者中,认知功能和运动控制之间存在潜在的联系.
研究的目的:
- 评估自我管理的认知康复计划对轻度至中度帕金森病患者的平衡和运动症状的影响.
- 在经过4周的认知训练干预后,评估认知功能,平衡和运动表现的变化.
主要方法:
- 进行了一项随机对照试验,39名参与者被诊断为轻度至中度PD (Hoehn和Yahr≤III) 并且没有认知障碍 (MoCA≥24).
- 参与者被随机分配到一个实验组 (n=20),通过NeuronUP平台接受认知训练,或一个没有接受干预的对照组 (n=19).
- 干预的重点是持续的注意力和信息处理速度,每天30分钟,每周3天,超过4周. 主要结局是伯格平衡量级 (BBS);次要结局包括UPDRS-III,%LOS,TUG,TMT-A,TMT-B,处理速度和Stroop测试.
主要成果:
- 认知干预组显示,通过UPDRS-III测量,运动症状严重程度的统计显著降低 (p=0.039).
- 在平衡中观察到边际改善,通过伯格平衡量表 (BBS) 进行评估 (p=0.053).
- 在其他评估的运动变量 (例如%LOS,TUG) 或认知功能 (例如TMT-A,TMT-B,处理速度,Stroop测试) 中没有发现显著改善.
结论:
- 在这项研究中实施的自我认知训练并没有提高帕金森病患者的平衡或认知能力.
- 干预导致运动症状严重程度显著下降,这表明PD运动功能的潜在益处.
- 需要进一步的研究来探索更密集或面对面的认知康复方案的有效性,特别是关于它们对PD平衡的影响.
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