粒状淋巴腺病和结核病:组织学准确性
Frédéric Méchaï1, Lou Macaux2, Florence Jeny3
1Department of Infectious Diseases, Avicenne Hospital, Hôpitaux Universitaires Paris Seine-Saint-Denis, Bobigny, France; IAME, INSERM UMR 1137, Université Paris Cité, Université Sorbonne Paris Nord, Paris, France.
组织学是确切的诊断结核病 (TB),特别是肺外结核病,即使微生物学测试是负面的. 颗粒瘤中的病菌性亡是结核病诊断的关键指标.
科学领域:
- 病理学 病理学 病理学
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 结核病 (TB) 的微生物学测试往往缺乏足够的灵敏度.
- 组织学可以帮助诊断结核病,特别是肺外形式.
- 表皮质粒瘤是淋巴结活检中常见的发现.
研究的目的:
- 评估结核病的组织学诊断性能,特别是表皮质颗粒瘤和结核病例性亡.
- 为了确定结核病诊断中的组织学发现的准确性,与微生物学方法相比.
主要方法:
- 2019-2023年淋巴结活检数据的回顾性分析.
- 鉴定表皮状颗粒瘤病例.
- 评估结核病病的存在及其与结核病诊断的相关性.
主要成果:
- 在220名患有上皮质粒瘤的患者中,有86人 (39%) 患有结核病,110人 (50%) 患有沙尔科发病,4人 (1.8%) 患有巴顿氏病.
- 在74个颗粒瘤中存在状缩,主要是结核病 (89%).
- 对于结核病的诊断,病例性缩显示了77%的灵敏度,94%的特异性,89%的PPV和86%的NPV.
结论:
- 淋巴结组织学检查是诊断结核病的可靠方法.
- 在颗粒瘤中出现状死是结核病的强有力的指标.
- 组织学使得在缺乏微生物学证据的可疑结核病例中,能够迅速启动概率治疗.
更多相关视频
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
09:58Spatial Quantification of Drugs in Pulmonary Tuberculosis Lesions by Laser Capture Microdissection Liquid Chromatography Mass Spectrometry LCM-LC/MS
Published on: April 18, 2018
相关概念视频
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
