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Updated: Aug 3, 2026

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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脂质体脂质纳米颗粒用于mRNA的肝外输送

Miffy Hok Yan Cheng1, Yao Zhang2,3,4, Kevin Fox2

  • 1Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. miffy.cheng@ubc.ca.

Nature communications
|May 3, 2025
PubMed
概括

新的脂质纳米粒子 (LNP) 系统具有高双层脂质含量,可以改善mRNA向肝外组织的输送. 这些脂质体LNP显示出更长的循环时间和增强的转染,这对于先进疗法至关重要.

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