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Updated: May 9, 2025

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions
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In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions

Published on: July 17, 2019

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EXO1通过与MLH1,MSH4和DNA的保守相互作用促进介质MLH1-MLH3内核酶

Megha Roy1, Aurore Sanchez2,3, Raphael Guerois4

  • 1Institute for Research in Biomedicine, Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Bellinzona, Switzerland.

Nature communications
|May 3, 2025
PubMed
概括

EXO1对于分解介质重组中间体至关重要. 它与MutSγ和MutLγ复合物的相互作用,而不是其核酶功能,是激活交叉形成期间DNA裂变的关键.

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