Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Retina01:32

The Retina

66.2K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
66.2K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

5.8K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
5.8K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

5.4K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Nationwide trends in outpatient rates for ophthalmic surgeries in Japan before and after the COVID-19 pandemic: an analysis of the NDB open data.

Scientific reports·2026
Same author

[Development of a manual for appropriate data collection and judgment in special health examinations].

Sangyo eiseigaku zasshi = Journal of occupational health·2026
Same author

Nationwide trends and regional variation in intravitreal injections and anti-VEGF agent use in Japan from 2017 to 2022: An analysis of the NDB Open Data.

PloS one·2026
Same author

Erlotinib-Induced Ocular Cicatricial Pemphigoid in EGFR-Mutated Non-Small Cell Lung Cancer: A Case Report.

Clinical lung cancer·2026
Same author

Accurate Prediction of Humphrey 10-2 Visual Fields in Glaucoma from a Single Rapid IMOvifa 24plus(1-2).

Ophthalmology science·2026
Same author

Association Between Occupation and Cancer Risk: A Large-Scale Case-Control Study in Japan.

Journal of occupational and environmental medicine·2026

相关实验视频

Updated: May 9, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.0K

隐藏的视网膜结构模式与衰老.

Kei Sano1,2, Kota Fukai3, Ryo Terauchi2

  • 1Department of Preventive Medicine, Tokai University School of Medicine, Isehara, Japan.

NPJ digital medicine
|May 3, 2025
PubMed
概括

光学连贯断层扫描 (OCT) 使用新型原型揭示与年龄相关的视网膜变化. 这些模式,包括斑点的稀薄,可能会增强生物标志物用于与年龄相关的疾病.

更多相关视频

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
08:54

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Published on: May 26, 2023

1.3K
Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

21.4K

相关实验视频

Last Updated: May 9, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.0K
Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
08:54

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Published on: May 26, 2023

1.3K
Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

21.4K

科学领域:

  • 眼科医生 眼科 眼科
  • 老年学是一门学科.
  • 生物医学成像技术 生物医学成像技术

背景情况:

  • 光学连贯断层扫描 (OCT) 不侵入性地评估视网膜结构.
  • 视网膜变薄是诸如阿尔茨海默氏症和帕金森症等全身性疾病的潜在生物标志物.
  • 与年龄相关的视网膜变化尚未完全理解,这阻碍了疾病的分化.

研究的目的:

  • 开发一种颗粒式方法来评估与年龄相关的视网膜内部空间变化.
  • 识别和描述与衰老相关的潜在视网膜原型.
  • 探索这些原型作为与年龄有关的疾病的生物标志物的实用性.

主要方法:

  • 利用了来自22494个人的189387个OCT扫描的大数据集.
  • 从斑点和外皮毛细节图像中开发了36种不同的视网膜原型.
  • 分析了原型和参与者的年龄之间的关联,包括近视子组分析.

主要成果:

  • 确定了与年龄相关的原型,其特点是斑点变薄 (总或高级).
  • 观察到黄斑的质细胞内状层的下层稀释与近视个体的衰老有关.
  • 发现与年龄相关的影响,表现为视网膜动脉轨迹形状的变化.

结论:

  • 潜在的视网膜原型为了解与年龄相关的视网膜变化提供了详细的方法.
  • 这些原型有望改善视网膜生物标志物的使用,用于诊断和监测与年龄相关的疾病.
  • 对视网膜原型的进一步研究可以解锁新的诊断和预后能力.