在NSCLC中,SMAD2链接物化影响总体存活率,增殖率,TGFβ1依赖基因表达和与多能性相关的蛋白质

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Updated: May 9, 2025

Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene
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Published on: December 31, 2014

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Dörte Nitschkowski1,2, Tim Vierbuchen3, Holger Heine4,3

  • 1Histology, Research Center Borstel - Leibniz Lung Center, Borstel, Germany. dnitschkowski@fz-borstel.de.

British journal of cancer
|May 3, 2025
PubMed
概括

化SMAD2链接剂 (pSMAD2L) 影响非小细胞肺癌 (NSCLC) 的进展. 瘤中的低pSMAD2L会使预后恶化,而免疫细胞中的低pSMAD2L会提高生存率.

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