α-Synuclein有针对性的治疗与多种病理改善帕金森病的宏环两类纳米医药

Jian-Mei Gao1, Wen-Bo Li2, Yang Yi1

  • 1School of Pharmacy, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, China.

Biomaterials
|May 4, 2025
PubMed
概括

一种新的GCA-CD纳米药物有效地抑制α-synuclein (α-Syn) 聚合并分解纤维素,这对于帕金森病 (PD) 治疗至关重要. 这种疗法通过恢复线粒体功能和减少氧化应激来拯救PD模型中的运动缺陷和神经退行.