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Updated: May 17, 2025

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纤维细胞激活蛋白向的仿真抗原受体修饰NK细胞缓解心脏纤维化

Qi Zheng1, Hao Li1, Yongliang Jiang2

  • 1Department of Cardiology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650101, China.

International immunopharmacology
|May 4, 2025
PubMed
概括

针对纤维细胞激活蛋白 (FAP) 的工程CAR自然杀手 (NK) 细胞有效地减少了小鼠的心脏纤维化. 这种新疗法通过消除FAP阳性细胞和改善心脏功能来治疗心血管疾病具有前景.

关键词:
心脏纤维化是什么心脏纤维化化学抗原受体的化学抗原受体纤维细胞激活蛋白质的激活蛋白质纤维细胞到肌纤维细胞的分化.免疫治疗是一种免疫疗法.自然杀手细胞是什么?

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