在干预性神经放射学中评估大脑和透镜辐射暴露
Mohamed Khaldoun Badawy1, Stanley Albert Norris2, Alice Gutowski2
1Monash Imaging, Monash Health, Clayton, Australia; Department of Medical Imaging and Radiation Sciences, Monash University, Melbourne, Australia.
概括
干预性神经放射学 (INR) 程序经常超过大脑辐射剂量值,累计暴露显著增加了风险. 镜片剂量值很少被超过,剂量区域产品 (DAP) 可靠地预测器官剂量.
科学领域:
- 医学物理 医学物理
- 放射学 放射学是指放射学
- 神经辐射学神经辐射学
背景情况:
- 干预性神经放射学 (INR) 程序涉及大量的辐射暴露.
- 评估大脑和透镜辐射剂量对于管理组织反应至关重要.
研究的目的:
- 在INR程序期间评估大脑和透镜辐射剂量.
- 为了确定器官吸收的累积剂量和超过组织反应值的风险.
主要方法:
- 对2668个成年INR程序的回顾性审计 (2018年1月 - 2024年6月).
- 用于剂量计算和模拟的剂量面积产物 (DAP) 和累积空气克尔玛 (CAK).
- 回归分析用于从DAP和CAK中预测大脑和透镜剂量.
主要成果:
- 18%的患者超过了0.5 Gy的大脑组织剂量值;<1%超过了透镜值.
- 78%的经过>2次手术的患者超过了大脑剂量值.
- DAP强烈预测的大脑 (R2=0.89) 和透镜 (R2=0.70) 的剂量.
结论:
- INR程序经常接近或超过大脑剂量值;透镜值风险很低.
- DAP是用于风险评估的器官剂量的可靠预测器.
- 在规划中考虑累积暴露;需要进一步研究长期结果.
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