对阿尔茨海默病认知功能的结果测量仪器的有效性和可靠性:系统性审查
Zhe-Zuo Zhang1,2, Xiao-Ying Lyu3, Xiang-Wei Dai3
1Institute of Basic Research In Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China, zhezuozhang@126.com.
Dementia and geriatric cognitive disorders
|May 4, 2025
概括
这次审查确定了用于选认知障碍和阿尔茨海默病 (AD) 的可靠工具. 建议使用ADAS-Cog和MoCA等尺度来评估AD患者的认知功能.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 心理测量 心理测量 心理测量
背景情况:
- 认知障碍和阿尔茨海默病 (AD) 需要精确的查工具.
- 现有的评估工具需要严格评估可靠性和有效性.
研究的目的:
- 系统地审查和确定认知障碍和AD查的验证评估工具.
- 评估认知功能评估仪器的可靠性和有效性.
主要方法:
- 对相关研究进行PubMed和CNKI数据库的系统文献搜索.
- 包括英语和中文研究报告认知功能尺度的开发或验证.
- 使用COSMIN标准和修改后的GRADE对评级测量属性的方法质量评估.
主要成果:
- 包括62篇文章,报告了49个认知障碍评估尺度.
- 发现AD评估尺度-认知子尺度 (ADAS-Cog),蒙特利尔认知评估 (MoCA) 和其他证明了足够的有效性和可靠性.
- 在不同研究中,方法质量和测量特性各不相同.
结论:
- 建议使用ADAS-Cog,MoCA,贝勒深度精神状态检查 (BPMSE),临床痴呆评级 (CDR) 和迷你精神状态检查来评估AD的认知障碍.
- 未来的规模开发应该考虑时间,语言和文化因素.
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