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Updated: May 9, 2025

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基于固态离子液体的甲福明配方,具有增强的GI上皮透度

Evangelia Tsolaki1, Fiona McCartney2, Anne Marie Healy3

  • 1School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland.

International journal of pharmaceutics
|May 4, 2025
PubMed
概括

使用喷雾封装固化活性药物成分-离子液体 (API-ILs) 的固化可改善处理并增强肠道药物吸收. 这种新的方法提高了生物可用性较差的药物的透性,克服了配方挑战.

关键词:
活性药物成分 - 离子液体乙烯基纤维素是一种乙烯基纤维素.拉布拉索尔 (Labrasol® ALF) 是一种基于脂质的配方甲胺是一种甲胺.甲福林化甲福林化这就是PeceolTM.透性 透性的喷雾封装的封装方式纤维素乙酸盐的使用情况酸盐的使用方法

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