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Updated: May 16, 2025

Analyzing Oxygen Consumption Rate in Primary Cultured Mouse Neonatal Cardiomyocytes Using an Extracellular Flux Analyzer
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老化中的NOX4驱动的线粒体氧化应激促进心肌重塑,并增加对心室动脉节律失常的易感性

Roberto Ramos Mondragon1, Shuyun Wang1, Mark D Stevenson2

  • 1Department of Pharmacology, University of Michigan, 1150 West Medical Center Dr., 2301 Medical Science Research Building III, Ann Arbor, MI, 48109, USA.

Free radical biology & medicine
|May 4, 2025
PubMed
概括

线粒体NADPH氧化酶4 (NOX4) 在心脏衰老中的过度表达增加了心室动脉节律失常 (VT) 的风险. 向NOX4可能会防止与年龄有关的心脏电气和结构变化,减少静脉动.

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