在男孩的前列腺体积与hypospadias基于跨腹部超声波
Kinga Kowalczyk1, Maria Szarras-Czapnik2, Elżbieta Marczak2
1Department of Pediatric Urology, Children's Memorial Health Institute, Warsaw, Poland.
Journal of pediatric urology
|May 4, 2025
概括
没有持续的米勒尔结构 (Ms) 的低血压的男孩显示前列腺大小正常. 然而,在某些年龄组中,那些患有低度和持续的穆勒尔结构 (HMs) 的人的前列腺显着较小.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 内分泌学 在内分泌学.
- 发展生物学 发展生物学
背景情况:
- 胎儿丸中的雄激素会影响外部生殖器和前列腺发育.
- 外部生殖器发育异常可能与前列腺发育问题相关.
研究的目的:
- 为了比较男孩的前列腺大小,不同程度的hypospadias.
- 调查持续的穆勒尔结构 (Ms) 对前列腺大小相对于年龄规范的影响.
主要方法:
- 涉及前列腺的跨腹部超声波 (TUS) 的前性研究.
- 对522名1至17岁的白人男孩进行了分析,其中126名患有低血压症.
- 低血压症的分类为轻度 (MH),严重 (SH) 和持久的米勒尔结构 (HMs) 的低血压症.
主要成果:
- 患有MH和SH的男孩通常的前列腺体积与年龄相关规范相比较.
- 在5-10岁和13-15岁年龄组的男孩中观察到明显较小的前列腺体积 (p<0.05).
- 在16-17岁的HM群中,观察到前列腺体积缩小的趋势 (p=0.054).
结论:
- 没有Ms的hypospadias没有导致前列腺体积显著偏离规范.
- 患有HMS的男孩在特定年龄组中表现出明显减少的前列腺体积,这是一个新发现.
- HMs的存在与儿科患者前列腺发育的改变有关.
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