在澳大利亚和加拿大的肺部低剂量计算机断层扫描癌症查期间的偶然发现, 2016-21:一项前性观察性研究
Asha Bonney1,2, Diane M Pascoe1,2, Mark W McCusker1,2
1Royal Melbourne Hospital, Melbourne, VIC.
The Medical journal of Australia
|May 4, 2025
概括
在低剂量计算机断层扫描 (LDCT) 肺癌查期间,偶然发现很常见. 需要标准化报告,以便对这些频繁发现进行一致的临床随访.
科学领域:
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
背景情况:
- 使用低剂量计算机断层扫描 (LDCT) 的肺癌查变得越来越普遍.
- 查期间的偶然发现可能会影响患者管理和医疗保健资源利用.
- 了解偶然发现的频率和类型对于优化查协议至关重要.
研究的目的:
- 确定在接受基线LDCT肺癌查的高风险个体中偶然发现的流行率和类型.
- 为了比较澳大利亚和加拿大参与者之间偶然发现的频率.
- 评估在临床报告中报告偶然发现的一致性.
主要方法:
- 一项前性观察性研究,是国际肺部查试验 (ILST) 的一个子研究.
- 包括来自澳大利亚和加拿大的4403名高风险参与者 (50-80岁),接受基线LDCT查.
- 使用研究检查清单确定了偶然发现,并由放射科医生进行分类;临床文件中的报告也得到了评估.
主要成果:
- 超过72%的参与者至少有一次偶然发现,其中10.3%需要临床随访.
- 最常见的发现是冠状动脉化 (69.0%) 和肺气 (54.0%).
- 在澳大利亚和加拿大地点之间观察到偶然发现的流行率和报告一致性的显著差异.
结论:
- 偶然发现在LDCT肺癌查中很常见,需要临床关注.
- 对这些发现的不一致报告需要采用标准化的方法.
- 建议在澳大利亚实施标准化报告模板,以确保对偶然发现的临床意义的明确指导.
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