PMN-MDSCs协调肺部的免疫抑制微环境,并与支气管切除症的临床结果有关

Jielin Duan1,2, Zhiwen Huang1,3, Ying Jiang4,5

  • 1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Department of Allergy and Clinical Immunology, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Respirology (Carlton, Vic.)
|May 4, 2025
PubMed
概括

在支气管切除症中,多态核核髓质衍生抑制细胞 (PMN-MDSCs) 在肺部积累,通过阿基因酶-1抑制免疫反应. 它们的水平与恶化相关,并随着抗生素治疗而改善.