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Updated: Aug 10, 2026

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
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硫化对α-synuclein聚合和细胞活力的作用

Elena A Ostrakhovitch1,2, Eun-Suk Song1,2, Johannah E Stegemann1,2

  • 1Department of Neurology, University of Kentucky, 740 South Limestone St., Ste. J401, Lexington, KY, 40536-0284, USA.

Scientific reports
|May 4, 2025
PubMed
概括

硫化 (H2S) 捐赠者,如硫化 (NaHS),显示出抑制α-synuclein (α-Syn) 聚合的潜力,这是帕金森病 (PD) 的关键因素. NaHS特别针对突变的α-Syn,减少有毒聚合物,并在PD模型中改善细胞活力.

关键词:
硫化是一种硫化.帕金森病是帕金森病的一种疾病.蛋白质聚合蛋白质的聚合.α-Synuclein 是一种蛋白质.

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