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Updated: May 12, 2026

Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
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NAMPT调节了小鼠早期胚胎发育中的线粒体和氧化应激水平

Mei-Hua Liao1, Xin Liu2, Xiao-Ting Yu1,2

  • 1Key Laboratory of Research on Clinical Molecular Diagnosis for High Incidence Diseases in Western Guangxi of Guangxi Higher Education Institutions, Reproductive Medicine of Guangxi Medical and Health Key Discipline Construction Project, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.

Biological research
|May 4, 2025
PubMed
概括

尼古丁胺胺酸基转移酶 (NAMPT) 对于小鼠胚胎早期发育至关重要. 抑制NAMPT会破坏细胞分裂,线粒体功能,并增加氧化应激和亡.

关键词:
在Actin中的Actin是Actin.线粒体中的线粒体.卵细胞是卵细胞中的一个.氧化应激是一种氧化应激.帕金森病是帕金森氏症的一种疾病.

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Measuring Mitochondrial Electron Transfer Complexes in Previously Frozen Cardiac Tissue from the Offspring of Sow: A Model to Assess Exercise-Induced Mitochondrial Bioenergetics Changes08:04

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相关概念视频

Translocation of Proteins into the Mitochondria01:19

Translocation of Proteins into the Mitochondria

Mitochondrial precursors are translocated to the internal subcompartments via independent mechanisms involving distinct protein machineries called translocases.
Sorting of outer membrane proteins:
Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...