加速度计衍生的"周末战士"和定期活跃的体力活动和事件糖尿病
Lubi Lei1, Jingkuo Li1, Wei Wang2
1National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Obesity (Silver Spring, Md.)
|May 5, 2025
概括
参与中度至强度的体力活动 (MVPA),即使是周末战士 (WW),也会显著降低糖尿病风险. 无论是WW还是定期活跃 (RA) 模式,与不活跃相比,它们都提供了相似的保护.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 运动科学 运动科学
背景情况:
- 糖尿病是一种主要的全球健康问题.
- 了解身体活动模式对糖尿病风险的影响对于预防策略至关重要.
- 以前的研究主要集中在每周的体力活动总量上,对活动在一周内如何分布的关注较少.
研究的目的:
- 研究不同模式的中度至强度体力活动 (MVPA) 与患糖尿病的风险之间的关联.
- 为了比较与"周末战士" (WW) 身体活动模式相关的糖尿病风险降低,与定期活跃 (RA) 和不活跃模式相比.
主要方法:
- 一项前性队列研究,涉及英国生物银行的85,934名参与者.
- 参与者被分为"周末战士" (WW),"经常活跃" (RA) 和"不活跃"基于MVPA水平 (≥150分钟/周或≥230.4分钟/周) 和分布 (≥50%的MVPA在1-2天内为WW).
- 考克斯的比例危险回归模型被用来分析MVPA模式和发病糖尿病之间的关联.
主要成果:
- 与不活动相比",周末战士" (WW) 身体活动模式与糖尿病风险降低有关 (HR:0.76,95% CI:0.69-0.84).
- "经常活跃" (RA) 模式也显示了糖尿病风险的显著降低 (HR:0.64,95% CI:0.56-0.73).
- 当使用基于指南和样本的MVPA.中位数值时,这些发现一致.
结论:
- "周末战士"的体育活动模式与"经常活跃"的模式相似,对糖尿病有着类似的保护作用.
- 达到建议的中度至强度体力活动水平,即使集中在更少的天数中,也有效降低糖尿病风险.
- 这些结果强调了体力活动量的重要性,无论其分布如何,对于预防糖尿病.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
471
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
471
Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
Carbohydrate Metabolism
10.5K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.5K
Diabetes Mellitus: Overview and Type I Subtype
2.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.3K
Insulin: Dosing Regimen and Adverse Effects
121
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
121
Pathophysiology of Diabetes
805
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
805


