患有急性心力衰竭的患者的慢性便秘与预后有关
Alberto Domínguez-Rodríguez1, Néstor Báez-Ferrer2, Pablo Avanzas3
1Departamento de Medicina Interna, Universidad de La Laguna, Tenerife, España. Servicio de Cardiología, Hospital Universitario de Canarias, Tenerife, España.
概括
由于急性心力衰竭 (AHF) 住院的患者的慢性便秘 (CC) 与更糟糕的短期结果有关. 这项研究发现,CC患者患30天死亡率或AHF再入院的风险更高.
科学领域:
- 心脏病学 心脏病学
- 胃肠病学 胃肠病学
- 内部医学 内部医学
背景情况:
- 急性心力衰竭 (AHF) 是住院的主要原因.
- 慢性便秘 (CC) 是老年患者常见的并发症.
- CC对AHF预后的影响尚不清楚.
研究的目的:
- 调查慢性便秘 (CC) 与急性心力衰竭 (AHF) 住院患者的短期预后之间的关联.
主要方法:
- 从AHF患者收集未来的数据.
- 根据已确定的症状标准 (≥2个症状≥3个月) 诊断出CC.
- 对30天死亡率或AHF再接收率的分析,有或没有倾向性得分匹配.
主要成果:
- 在492名AHF患者中,有23.6%患有CC.
- 慢性病患者表现出更高的并发病率 (慢性功能衰竭,心脏膜疾病,心房动) 和需要机械通风.
- 卡普兰-梅尔分析显示,CC患者的30天死亡率或AHF再入院风险显著增加 (匹配后P<0.05).
结论:
- 慢性便秘与急性心力衰竭住院患者的临床结果较差有关.
- 在AHF患者中识别和管理CC可能会改善短期预后.
- 需要进一步的研究来探索将CC和AHF结果联系在一起的机制.
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