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Updated: May 9, 2025

Screening for Melanoma Modifiers using a Zebrafish Autochthonous Tumor Model
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在黑色素瘤中,ZNF224通过p53和AKT通路增强了p21的致癌功能

Leandra Sepe1, Umberto Candia1, Dario Sasso Del Verme1

  • 1Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.

The FEBS journal
|May 5, 2025
PubMed
概括

指蛋白224 (ZNF224) 通过增强p21 ((CIP1/WAF1) 活性来驱动黑色素瘤的进展. 这项研究揭示了ZNF22424的存在.

关键词:
在 AKT 激酶中,有 AKT 激酶.在 ZNF22424 中.黑色素瘤是一种黑色素瘤.p21 瘤基因发生的原因在 p53 里,p53 是一个 p53 号码.

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