粉样PET长期召回结果的结果
Maria Scanlan1, Hunter Heigert1, Ryan A Townley1
1University of Kansas Alzheimer's Disease Research Center, University of Kansas Medical Center, Department of Neurology, Fairway, KS.
概括
大多数成年人几年后都记得他们的粉样蛋白PET扫描结果. 虽然行为变化很小,但参与者准确地感知了他们的阿尔茨海默病风险,没有持久的痛苦,支持披露的可接受性.
科学领域:
- 神经成像是一种神经成像.
- 认知神经学 认知神经学
- 阿尔茨海默氏症疾病研究研究
背景情况:
- 粉样蛋白PET成像对于诊断阿尔茨海默病 (AD) 是至关重要的.
- 了解披露粉样蛋白PET结果的长期影响对于临床实践很重要.
- 评估患者的召回和心理影响为基因和生物标志物测试的伦理准则提供了信息.
研究的目的:
- 为了评估粉样PET的长期回忆结果.
- 评估这些结果对参与者的行为和心理健康的感知影响.
- 为了确定粉样蛋白PET的长期可接受性,在认知正常的个体中披露结果.
主要方法:
- 在对92名认知正常的成年人进行了一项调查,在他们的粉样蛋白PET结果结构化披露6-9年后进行了调查.
- 收集的数据包括结果回忆精度,报告的行为变化,感知AD风险和心理痛苦.
- 统计分析检查了扫描结果和报告结果之间的关系.
主要成果:
- 三分之二的参与者正确地回忆起他们的粉样蛋白PET结果.
- 只有三名参与者错误地记住了他们的结果,因为它们与所传达的结果相反.
- 大多数参与者报告的行为变化有限,尽管那些高扫描的人更有可能采用生活方式修改.
- 感知AD风险与扫描状态相关,但没有导致显著的持久心理痛苦.
- 大多数参与者认为披露经验是积极的,并会重复测试.
结论:
- 粉样蛋白PET结果通常被认知正常的个体长期记住.
- 粉样蛋白PET结果的披露似乎是可以接受的,并且通常不会导致持久的心理痛苦.
- 这些发现支持在临床环境中继续使用结构化粉样蛋白PET结果披露.
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