代谢功能障碍的未满足需求 - 相关的"脂肪或脂肪性"肝病
Yu-Ming Cheng1, Shao-Wen Wang2, Ching Wang3
1Department of Gastroenterology and Hepatology, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan.
Tzu chi medical journal
|May 5, 2025
概括
非酒精性脂肪性肝病 (NAFLD) 正在被新术语取代,如代谢功能障碍相关的脂肪性肝病 (MAFLD) 和代谢功能障碍相关的脂肪性肝病 (MASLD). 本综述探讨了这些不断变化的肝病分类的优缺点.
科学领域:
- 肝病学和胃肠道学
- 代谢障碍 代谢障碍 代谢障碍
- 肝脏疾病名称表格 肝脏疾病名称表格
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是最常见的慢性肝病,带来了重大的健康和经济挑战.
- 通过排除来诊断NAFLD,缺乏特定的病因学标准.
- 最近的建议包括代谢功能障碍相关的脂肪肝病 (MAFLD) 和代谢功能障碍相关的脂肪性肝病 (MASLD),以改进诊断.
研究的目的:
- 批判性地评估NAFLD:MAFLD和MASLD的拟议替代术语.
- 根据当前的科学证据,分析MAFLD和MASLD的优缺点.
- 促进未来关于肝病命名的全球共识.
主要方法:
- 审查当前的科学文献和关于NAFLD,MAFLD和MASLD的研究证据.
- 对诊断标准和每个术语的含义进行比较分析.
- 评价命名对医学沟通和研究进展的影响.
主要成果:
- 作为排除诊断的NAFLD的定义存在局限性.
- MAFLD引入了代谢功能障碍标准,而 MASLD 包含了心脏代谢因素,避免了对语言的污名化.
- 不同的命名法 (MAFLD与MASLD) 在医学界创造了沟通挑战.
结论:
- 从NAFLD到MAFLD和MASLD的演变反映了不断努力提高诊断准确性和对肝病的理解.
- 解决MAFLD和MASLD之间的分歧对于推进研究和临床实践至关重要.
- 建立与代谢功能障碍相关的肝病的统一命名体系对于未来的进展至关重要.
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