为嵌入式实用临床试验招募临床场所的新方法:来自AIM支持试验的见解
Tyler L Cope1,2, Steven Z George1,2,3, S Nicole Hastings2,4,5
1Duke Clinical Research Institute, Durham, NC, USA.
Contemporary clinical trials communications
|May 5, 2025
概括
为嵌入式实用临床试验 (ePCT) 招募临床场所可能是复杂的. 该AIM-Back试验成功招募了19个网站,使用三步方法,为未来的研究提供了洞察力.
科学领域:
- 临床试验 临床试验
- 医疗保健服务研究 医疗服务研究
- 实用临床试验 实用临床试验
背景情况:
- 嵌入式实用临床试验 (ePCT) 对于实际干预评估至关重要.
- 招募ePCT临床场所的最佳实践,特别是新建的临床场所,尚未得到很好的认可.
- 该AIM-Back试验的重点是招募退伍军人健康管理局 (VA) 内的网站,以进行腰部疼痛干预.
研究的目的:
- 描述AIM-Back嵌入式实用临床试验的场地招聘过程.
- 识别挑战和成功的战略,以招募不熟悉研究的临床场所.
- 在未来的ePCT中为招聘网站提供一个模型.
主要方法:
- 采用了三步招聘方法:领先的识别,领先的参与和虚拟会议.
- 通过VA联系人,数据库和外展活动确定了潜在的地点.
- 招聘涉及VA医疗保健系统的临床医生,管理人员和领导.
主要成果:
- 在53个VA医疗保健系统中识别了184个潜在客户,其中40个系统响应了外展.
- 招聘会议与23个系统举行,导致19个站点的参与协议.
- 从外展到协议的中位数招聘时间是3.7个月; 常见的障碍包括资源限制和竞争性计划.
结论:
- 在AIM-Back的招聘过程中,强调了吸引新的ePCT临床研究站点的复杂性.
- 在类似的试验中,一个结构化,三步的招聘策略可以有效.
- 未来的ePCT应优先考虑全面的战略,以确保临床医生的参与和研究可行性.
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