血液制品在胃肠道出血中的血栓形成显微镜辅助输血中的利用:一个单一中心的经验
Mohammad Abdulelah1, Aleezay Asghar2, Michael Sansait3
1Department of Internal Medicine, Baystate Medical Center, University of Massachusetts Chan Medical School, Springfield, MA 01199, USA.
Gastroenterology research
|May 5, 2025
概括
在胃肠道出血 (GIB) 复苏过程中使用血栓结晶造影 (TEG) 并没有明显降低高死亡率. 需要进一步的研究来评估TEG.
科学领域:
- 关键护理医学 关键护理医学
- 血液学 血液学 血液学
- 胃肠病学 胃肠病学
背景情况:
- 胃肠道出血 (GIB) 是重症监护室 (ICU) 住院的常见原因,死亡率高.
- 在GIB的程序干预之前,有效的复苏至关重要.
- 血栓形成显微镜 (TEG) 评估了凝血,但其在GIB管理中的作用仍在争论中.
研究的目的:
- 评估TEG在GIB复苏期间的临床效用.
- 评估TEG对血液产品使用和GIB患者治疗结果的影响.
主要方法:
- 在GIB复苏期间接受TEG的ICU患者的回顾性研究 (2017-2020).
- 通过ICD-10代码和血液银行记录识别的患者数据.
- 对人口统计,并发病,复苏参数,输血产品,ICU住院和死亡率的分析.
主要成果:
- 分析了226名GIB患者 (平均年龄为61) 的队列.
- 常见的并发病包括酒精性肝病和食道静脉.
- 患者接受的红细胞中位数为5个包装红细胞 (pRBC) 和1个新鲜冷血 (FFP).
- 尽管使用TEG,但观察到的死亡率为39%.
结论:
- 由于高死亡率,TEG在减少GIB输血方面的好处是不确定的.
- 需要进一步的研究来确定TEG导向输血策略在GIB患者的疗效.
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