从自发双胞胎贫血多细胞瘤序列的快速变化到双胞胎对双胞胎输血综合征
Kenji Horie1, Katsusuke Ozawa2, Takafumi Okusa1
1Department of Obstetrics and Gynecology, Jichi Medical University, Shimotsuke, JPN.
Cureus
|May 5, 2025
概括
这项案例研究揭示了双胞胎贫血多细胞瘤序列 (TAPS) 到双胞胎输血综合征 (TTTS) 的罕见进展. 早期诊断和干预对于这些复杂怀孕的良好结果至关重要.
科学领域:
- 周围生理学 周围生理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 高风险的妇产科 高风险的妇产科
背景情况:
- 单胆子双胞胎有患胎盘血管瘤的风险.
- 双胞胎贫血多细胞瘤序列 (TAPS) 是一种罕见的并发症,其特征是血红蛋白水平不一致.
- 从TAPS向双胞胎输血综合征 (TTTS) 的进展非常罕见.
研究的目的:
- 描述一种自发TAPS的新奇自然过程.
- 在TAPS诊断后报告TTTS的快速发展.
- 突出TAPS怀孕中警监测的重要性.
主要方法:
- 基于中脑动脉峰值缩速度 (MCA-PSV) 不一致的TAPS的诊断.
- 诊断TTTS (昆特罗第一阶段) 基于羊水体积异常.
- 用胎儿镜激光光凝血治疗胎盘解剖的治疗.
主要成果:
- 自发性TAPS是在怀孕24+2周时被诊断出来的.
- 在四天内,病情进展为TTTS (昆特罗第一阶段).
- 在激光治疗后,两个双胞胎在33+0周出生时没有贫血或多细胞血症.
结论:
- 这一案例是TAPS在几天内迅速发展为TTTS的首例.
- 胎镜激光光凝血在控制进展方面是有效的.
- 密切监测对于识别和管理高风险双胞胎怀孕的快速变化至关重要.
更多相关视频
相关概念视频
Blood Transfusion and Agglutination
10.6K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.6K
Blood Transfusion
425
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
425
Tissue Transplantation
271
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
271
Disorders of Erythrocytes
722
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
722
Bone Marrow Sampling and Transplants
260
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
260
Erythropoiesis
3.9K
Red blood cells (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia,...
3.9K


