维生素和食补充剂在癌症治疗中:是否需要增加使用量?
Teresa Esposito1, Francesca Pentimalli2, Antonio Giordano3,4
1Department of Clinical Dietetics and Metabolic Diseases, Cavalier Raffaele Apicella Hospital, ASL Napoli 3 Sud, Naples, Italy.
Expert review of anticancer therapy
|May 5, 2025
概括
维生素对健康至关重要,但目前的证据显示,补充剂或饮食改变对癌症患者没有显著的益处. 需要监管,以确保产品的安全性和有效性.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 分子生物学分子生物学
背景情况:
- 维生素是必不可少的微量营养素,对生物体的平衡和正常功能至关重要.
- 它们通过抗氧化剂和辅因子功能,免疫反应,表观遗传调节和微生物群调节来预防瘤发病.
- 肥胖与不良饮食和不活动有关,增加癌症风险,而癌症患者经常面临维生素缺乏.
研究的目的:
- 批判性地分析关于维生素补充和饮食干预措施的临床前和临床研究,以预防癌症和患者护理.
- 阐明当前干预措施的局限性,并提出最佳饮食策略.
- 提高癌症患者的生活质量和预后.
主要方法:
- 来自PubMed和ClinicalTrials.gov.gov的临床前和临床研究的系统审查.
- 分析有关维生素补充剂,间歇性禁食和性饮食的数据.
- 对小鼠瘤模型和人类癌症患者的干预措施的评估.
主要成果:
- 临床研究表明,非处方维生素补充剂或饮食干预措施对癌症患者的健康和预后没有实质性的益处.
- 临床前数据和特定的饮食策略需要进一步严格调查.
- 目前的证据不支持广泛使用这些干预措施来治疗或预防癌症.
结论:
- 缺乏实质性证据支持当前维生素补充剂和饮食干预措施在改善癌症患者治疗结果方面的有效性.
- 监管机构对于监督营养药行业,确保产品质量和防止无效或有害产品的传播至关重要.
- 需要进一步的研究,以建立基于证据的饮食策略,以预防癌症和支持患者.
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