在COVID-19感染和接种疫苗后的状平原. 匹配的案例与对照研究
Paolo Giacomo Arduino1, Alexey Kubanov2, Anna Vlasova3
1Department of Surgical Science, University of Turin, Turin, Italy.
The Australasian journal of dermatology
|May 5, 2025
概括
COVID-19 感染和接种疫苗与新发平 (LP) 有着强烈的关联. 这表明COVID-19相关事件,特别是感染,可能会触发LP的发展.
科学领域:
- 皮肤病学 皮肤病学
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 报告显示,在COVID-19感染或接种疫苗后,有新发的平淡 (LP).
- 案例系列不足以进行暴露结果关联研究.
研究的目的:
- 调查COVID-19相关事件与新生平 (LP) 之间的关联.
主要方法:
- 匹配的病例控制研究设计.
- 包括组织学证实,新诊断的LP患者和匹配的对照.
- 排除已知LP触发因子的病例/对照.
- 在诊断前一个月内评估COVID-19感染 (PCR确认) 和接种疫苗 (病毒载体).
- 使用有条件和无条件逻辑回归进行分析.
主要成果:
- 分析了55个病例对照对.
- 在COVID-19相关事件和LP之间发现了显著的关联 (OR 7.50,95% CI 1.72-32.80;OR 4.45,95% CI 1.63-12.15).
- 亚组分析证实了与症状性COVID-19感染的相关性.
结论:
- 在COVID-19感染/接种疫苗和de novo LP之间存在强烈的显著关联.
- 与COVID-19相关的事件,特别是感染,可能会起到平的触发作用.
更多相关视频
08:04Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
15.6K
06:03Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
Published on: September 20, 2024
1.1K
相关概念视频
Factors Affecting the Risk of Infection
10.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
10.5K
Vaccinations
43.0K
Overview
43.0K
Single Nucleotide Polymorphisms-SNPs
13.6K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
13.6K
