周末追赶睡眠与糖尿病病风险之间的关系
Xia Wu1, Yunhai Tang1, Yayun He1
1Department of Nephrology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.
Archives of endocrinology and metabolism
|May 5, 2025
概括
周末补时睡眠 (WCS) 可能会降低糖尿病病 (DKD) 和糖尿病成人蛋白尿的风险. 这种益处在妇女和高血压患者中尤其明显.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
背景情况:
- 糖尿病病 (DKD) 是糖尿病的一个主要并发症.
- 睡眠障碍在糖尿病患者中很常见,可能会影响DKD风险.
- 周末追赶睡眠 (WCS) 在DKD发展中的作用尚不清楚.
研究的目的:
- 调查周末补时睡眠 (WCS) 与糖尿病病 (DKD) 风险之间的联系.
- 为了检查WCS与糖尿病成年人减少估计的膜过率 (eGFR) 和蛋白尿之间的关系.
主要方法:
- 一项采用来自国家健康和营养检查调查 (2017-2020) 的1621名成年人的数据进行的横截面研究.
- WCS计算为周末平均睡眠时间减去周日平均睡眠时间.
- 使用加权多变量逻辑回归和子组分析 (性别,高血压) 来评估关联.
主要成果:
- 2小时至3小时以下的WCS与较低的DKD (OR=0.51) 和蛋白尿 (OR=0.51) 的几率有关.
- 亚组分析显示,女性糖尿病患者和高血压患者之间存在显著的关联.
- 在WCS和降低的eGFR之间没有发现显著的关联.
结论:
- 周末补时睡眠可能是成年糖尿病患者防治DKD和蛋白尿的保护因素.
- 在女性和患有高血压的个体中,WCS的有益影响更为明显.
- 需要进一步的研究来证实这些发现,并探索潜在的机制.
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