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患者报告的症状负担与恶性肠道阻塞治疗方式相关
Sarah B Bateni1,2, Calvin H L Law1,3, Ashlie Nadler1
1Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
患有恶性肠道阻塞 (MBO) 的患者随着时间的推移经历了症状改善,手术提供了稍微更好的食欲和疼痛缓解. 这表明手术可能为选择的MBO患者提供息益处.
科学领域:
- 在瘤学瘤学.
- 抚慰性护理是一种缓解性护理.
- 手术瘤学手术瘤学
背景情况:
- 对恶性肠道阻塞 (MBO) 的最佳息治疗缺乏关于患者报告结果的强有力的证据.
- 在MBO干预后缓解症状的研究是有限的.
研究的目的:
- 为了比较患者报告的因恶性肠道阻塞 (MBO) 住院后的结果.
- 评估MBO手术,程序和医疗干预的结果.
主要方法:
- 在加拿大安大略省 (2010-2019) 的1,749名MBO患者患有无法治愈的癌症的人口层面分析.
- 使用前性收集的埃德蒙顿症状评估系统 (ESAS) 评分.
- 采用混合线性模型来比较MBO入院后1至6个月的症状得分.
主要成果:
- 在MBO住院之前和之后,中度至严重的症状 (疼痛,疲劳,缺乏幸福感,食欲) 普遍存在.
- 在所有患者中,在6个月期间观察到中度至重度症状的减少.
- 与医疗护理相比,手术干预与随着时间的推移,食欲和疼痛症状的减少更大.
结论:
- 住院患有MBO的患者报告症状随着时间的推移而有所改善,无论治疗方式如何.
- 手术干预可能提供息效益,特别是在选择的MBO患者中缓解食欲和疼痛症状.
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