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在口服药片中蛋白质和多糖类辅料之间的兼容性

Meng-Jia Jin1,2, Zhen-Yi Jing1,2, Li-Duo Liu1,3

  • 1Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Molecular pharmaceutics
|May 5, 2025
PubMed
概括

碳甲基粉 (CMS) 与特拉斯图祖马布 (TRA) 等蛋白质发生静电相互作用,降低可溶性蛋白质度. 这种取决于pH值的相互作用表明,CMS具有持续释放口服蛋白质生物制药的潜力.

关键词:
生物制药药片 生物制药药片静电相互作用 静电相互作用一种单克隆抗体,一种单克隆抗体.聚糖是一种多糖.蛋白质蛋白质是一种蛋白质蛋白质.碳素甲基粉 碳素甲基粉

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