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Updated: Jun 23, 2026

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肠上芯片平台:在先进的胃肠道研究中弥合体外和体内模型

Awurama Ofori-Kwafo1, Indira Sigdel1, Earshed Al Mamun1

  • 1Department of Bioengineering, College of Engineering, University of Toledo, Toledo, Ohio, USA.

Physiological reports
|May 5, 2025
PubMed
概括

肠上芯片技术通过模仿肠道复杂环境来推进胃肠道 (GI) 研究. 这些微流体模型改善了药物发现和针对胃肠道疾病的个性化药物.

关键词:
胃肠道的胃肠道是什么肠-大脑轴是什么意思在一个芯片上的肠.肠道模型 肠道模型微生物组是一个微生物组.

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iChip01:24

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...