流量转移与卷积在中小规模的近端前部循环的未破裂动脉瘤与复杂的解剖学:一个匹配对研究
Anton Gorbatykh1, Dmitry Kislitsin2, Timur Shayakhmetov2
1E. N. Meshalkin National Medical Research Center, Novosibirsk, Russian Federation. antonosjn@mail.ru.
Clinical neuroradiology
|May 5, 2025
概括
流量转移 (FD) 提供了较高的总封闭率和较少的手术内并发症前部循环动脉瘤与内血球卷曲 (EC) 相比. 两种治疗都显示出类似的神经风险,FD被认为是一种潜在的更安全,更有效的选择.
科学领域:
- 神经外科 神经外科
- 干预性神经辐射学
- 血管神经学 血管神经学
背景情况:
- 流量转移 (FD) 和内分泌绕 (EC) 对小到中等近道前部循环囊动脉瘤的比较疗效尚未确定.
- 本研究通过比较FD和EC结果来解决缺乏确定的证据的问题.
研究的目的:
- 为了比较FD与EC在治疗特定类型的大脑动脉瘤的疗效和安全性.
- 确定影响FD和EC治疗方式之间的选择因素.
主要方法:
- 追溯分析154个FD和190个EC病例,前部循环中的动脉瘤 (4-14毫米).
- 匹配的队列分析 (每例67例),控制动脉瘤特征和患者因素.
- 对94.2%的病例进行随访血管造影 (DSA),平均9个月.
主要成果:
- 在匹配的队列中,流量转移 (FD) 实现了较高的总封闭率 (80.3%),而不是内分泌绕 (EC) (49.2%).
- 在FD中,术后不良事件 (9%与22.4%,p=0.032) 和再治疗率 (1.5%与未指明,p<0.001) 显著降低.
- 神经性发病率和死亡率在FD和EC之间是可比的.
结论:
- 流量转移 (FD) 在实现全动脉瘤封闭方面表现出卓越的疗效,并且与内分泌绕 (EC) 相比,在手术内发生事件方面提高了安全性.
- 诸如子大小,眼膜位置,动脉瘤多重性和内置动脉分支等因素影响了FD的选择.
- 结合的动脉分支与不完全的阻塞有关,无论治疗方式如何.
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