在美国中西部两个城市的社区样本中,当前的暴露前预防 (PrEP) 用户,以前的使用者和非使用者之间的差异:促进PrEP摄入和坚持的干预措施的影响
Wayne DiFranceisco1, Katherine Quinn1, Jennifer L Walsh1
1Center for AIDS Intervention Research (CAIR), Medical College of Wisconsin, Milwaukee, Wisconsin.
概括
与男性发生性关系的黑人男性 (MSM) 和变性人和性别不符合 (TGW) 个体的艾滋病毒发病率更高. 这项研究发现PrEP (暴露前预防) 知识和积极态度是采用和坚持的关键.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 行为科学 行为科学
背景情况:
- 与男性发生性关系的黑人男性 (MSM) 和跨性别和性别不符合 (TGW) 人群之间存在艾滋病毒感染率的显著差异.
- 对有针对性的干预措施至关重要,以解决这些关键人口中采用暴露前预防 (PrEP) 的障碍.
研究的目的:
- 根据影响 PrEP 采用 PrEP 的态度和行为因素,比较目前使用,以前使用和从未使用 PrEP 的个人.
- 确定与有效遵守PrEP方案相关的因素.
- 探索前PrEP用户作为同行行为改变代理人的潜力.
主要方法:
- 对PrEP使用者群体 (现有,以前的,非使用者) 的比较分析.
- 回归分析以确定准备剂的采用和坚持的预测因素.
- 评估与PrEP相关的知识,态度,感知的耻辱和性行为.
主要成果:
- 与非使用者相比,现有和前PrEP使用者表现出明显更高的PrEP知识,并更多地沟通PrEP的好处.
- 前使用者报告了更积极的态度和与PrEP使用相关的较低的耻辱感.
- 目前的用户从事高风险的性行为 (无避孕套的门性行为,多个伴侣),而前用户更可能处于一夫一妻制的关系中.
结论:
- 研究结果支持预防有效坚持的概念,强调了知识和积极态度对持续使用PrEP的重要性.
- 前PrEP使用者可能在未来的艾滋病毒预防计划中成为有价值的同行教育者和行为改变代理人.
- 干预措施应侧重于增强PrEP知识,培养积极态度,减少耻辱,以改善黑人MSM和TGW的采用和坚持.
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