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Updated: May 9, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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伊塔科纳酸通过NRF2诱导增强肝脏葡萄糖生成.

Marwa O El-Derany1,2, Sadeesh K Ramakrishnan1, Yingjie Li1

  • 1Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America.

PloS one
|May 5, 2025
PubMed
概括

伊塔科纳酸是一种免疫代谢物,通过激活NRF2,独立于胰岛素,在禁食期间促进肝脏葡萄糖的产生. 这表明itaconate在代谢性肝病中的作用.

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