从1990年到2021年,60岁及以上的成年人中缺血性中风的全球负担:基于人口的研究研究
Xiuen Chen1,2, Lizhi Lu3, Chao Xiao2
1Department of Neurology, Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi Province, China.
PloS one
|May 5, 2025
概括
人口老龄化导致缺血性中风 (IS) 的负担日益增加. 这项研究强调了针对性预防和控制策略的关键需要,以减轻全球老年人IS风险.
科学领域:
- 全球卫生流行病学
- 老年医学 老年医学
- 神经学 神经学
背景情况:
- 缺血性中风 (IS) 构成了重大的公共卫生挑战,特别是在老年人群中.
- 关于60岁及以上个体的全球IS负担的综合数据有限.
- 了解IS流行,发病率,死亡率和残疾的趋势对于公共卫生规划至关重要.
研究的目的:
- 从1990年到2021年,评估60岁及以上的成年人中缺血性中风 (IS) 的全球负担.
- 分析与IS相关的流行,发病率,死亡率和残疾调整寿命年 (DALYs) 的趋势.
- 确定IS负担中的关键风险因素和人口差异.
主要方法:
- 利用了2021年全球疾病,伤害和风险因素负担研究的数据.
- 估计年平均百分比变化以分析年龄标准化利率的时间趋势.
- 在60岁以上的成年人中分析了缺血性中风的流行率,发病率,死亡率和DALYs.
主要成果:
- 人口老龄化是增加IS患病率和发病率的主要驱动因素.
- 与老年女性相比,老年男性的IS负担显著更高 (26-35%的更高率).
- 医疗服务负担的健康不平等正在扩大,较不发达地区受到了不成比例的影响.
结论:
- 人口老龄化是导致缺血性中风负担上升的主要因素.
- 有效预防和控制IS仍然是关键的公共卫生优先事项.
- 针对可修改风险因素的有针对性的干预措施对于降低全球IS负担至关重要.
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