对构成关系和变异配方的比较研究,用于建模胃肠周位素
Swati Sharma1, Martin Lindsay Buist1
1Department of Biomedical Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117583, Singapore.
概括
这项研究确定了胃肠道 (GI) 周围的最佳计算模型. 无法压缩的汉弗里.
科学领域:
- 计算力学是计算力学.
- 生物医学工程 生物医学工程
- 胃肠道生理学 胃肠道生理学
背景情况:
- 胃肠道 (GI) 周立体模拟对于理解消化至关重要.
- 有限元 (FE) 方法提供了一个强大的框架来模拟透.
- 准确的构成模型和可变配方是需要在GI组织的大变形.
研究的目的:
- 评估GI组织特征的组成模型.
- 确定最合适的FE方法来建模GI周围.
- 为了应对大变形和数值不稳定的挑战.
主要方法:
- 检查了几乎和纯不可压缩的构成模型.
- 研究了FE配方的各种变化原理.
- 使用了不可压缩的汉弗雷材料模型和两场配方.
主要成果:
- 汉弗莱的不可压缩的物质模型准确地重现了实验观测.
- 两场公式被证明足以建模大变形.
- 开发的FE模型在复制应力-应变数据方面实现了高精度 (R2>0.99).
结论:
- 不压缩的汉弗雷模型和双场FE配方非常适合用于胃肠道组织的表征.
- 这种方法可以准确的计算建模肠道周位形成.
- 这些发现推动了对胃肠道功能的预测模型的开发.
更多相关视频
相关概念视频
Gastric Motility
214
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
214
Structure and Organization of Smooth Muscles
4.9K
Smooth muscle tissue is a type of muscle tissue that can be found lining various vital organs in the human body, including the lungs, blood vessels, digestive tract, and respiratory tract. This type of tissue is responsible for regulating the movements of these organs, playing crucial roles in the functioning of various systems, including the vascular, digestive, respiratory, and urinary systems.
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
4.9K
Mechanical Systems
152
Mechanical systems are analogous to to electrical networks where springs and masses play similar roles to inductors and capacitors, respectively. A viscous damper in mechanical systems functions similarly to a resistor in electrical networks, dissipating energy. The forces acting on a mass in such systems include an applied force in the direction of motion, counteracted by forces from the spring, a viscous damper, and the mass's acceleration. This interplay of forces is mathematically...
152
Functions of Smooth Muscles
1.1K
Smooth muscles are an important type of muscle tissue that plays a vital role in the involuntary movements of internal organs. For example, they help regulate the movement of food through the gut and the flow of blood through the circulatory system.
Function of visceral smooth muscles
Visceral smooth muscle is found in the walls of all hollow organs, except the heart, and is a key player in the involuntary movements that drive the functioning of these internal organs. This tissue is arranged in...
Function of visceral smooth muscles
Visceral smooth muscle is found in the walls of all hollow organs, except the heart, and is a key player in the involuntary movements that drive the functioning of these internal organs. This tissue is arranged in...
1.1K
Typical Model Studies
147
Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
147
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
28
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
28


